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Two-Variance-Component Model Improves Genetic Prediction in Family Datasets
Genetic prediction based on either identity by state (IBS) sharing or pedigree information has been investigated extensively with best linear unbiased prediction (BLUP) methods. Such methods were pioneered in plant and animal-breeding literature and have since been applied to predict human traits, w...
Gespeichert in:
| Veröffentlicht in: | Am J Hum Genet |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667134/ https://ncbi.nlm.nih.gov/pubmed/26544803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.10.002 |
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