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Single Turnover Reveals Oxygenated Intermediates in Toluene/o-Xylene Monooxygenase in the Presence of the Native Redox Partners

Toluene/o-xylene monooxygenase (ToMO) is a non-heme diiron protein that activates O(2) for subsequent arene oxidation. ToMO utilizes four protein components, a catalytic hydroxylase (ToMOH), a regulatory protein (To-MOD), a Rieske protein (ToMOC), and a reductase (ToMOF). Here, we examine O(2) activ...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Liang, Alexandria Deliz, Lippard, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666740/
https://ncbi.nlm.nih.gov/pubmed/26267757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07055
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