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Mechanistic Studies of Reactions of Peroxodiiron(III) Intermediates in T201 Variants of Toluene/o-Xylene Monooxygenase Hydroxylase

Site-directed mutagenesis studies of a strictly conserved T201 residue in the active site of toluene/o-xylene monooxygenase hydroxylase (ToMOH) revealed that a single mutation can facilitate kinetic isolation of two distinctive peroxodiiron(III) species, designated T201(peroxo) and ToMOH(peroxo), du...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Song, Woon Ju, Lippard, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116272/
https://ncbi.nlm.nih.gov/pubmed/21595439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200340f
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