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Insights into the different dioxygen activation pathways of methane and toluene monooxygenase hydroxylases

The methane and toluene monooxygenase hydroxylases (MMOH and TMOH, respectively) have almost identical active sites yet the physical and chemical properties of their oxygenated intermediates, designated P(*), H(peroxo), Q and Q(*) in MMOH and ToMOH(peroxo) in ToMOH, are substantially different. We r...

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Detalhes bibliográficos
Main Authors: Bochevarov, Arteum D., Li, Jianing, Song, Woon Ju, Friesner, Richard A., Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092846/
https://ncbi.nlm.nih.gov/pubmed/21517016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110287y
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