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Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1–RanGTP–SPN1–Nup214 quaternary nuclear export complex
High conformational flexibility is an intrinsic and indispensable property of nuclear transport receptors, which makes crystallization and structure determination of macromolecular complexes containing exportins or importins particularly challenging. Here, the crystallization and structure determina...
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Publicado no: | Acta Crystallogr F Struct Biol Commun |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666476/ https://ncbi.nlm.nih.gov/pubmed/26625290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15021524 |
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