Base-resolution detection of N(4)-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing

Restriction-modification (R-M) systems pose a major barrier to DNA transformation and genetic engineering of bacterial species. Systematic identification of DNA methylation in R-M systems, including N(6)-methyladenine (6mA), 5-methylcytosine (5mC) and N(4)-methylcytosine (4mC), will enable strategie...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Yu, Miao, Ji, Lexiang, Neumann, Drexel A., Chung, Dae-hwan, Groom, Joseph, Westpheling, Janet, He, Chuan, Schmitz, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Methods Online
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666385/
https://ncbi.nlm.nih.gov/pubmed/26184871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv738
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