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Profiling tissue-resident T cell repertoires by RNA sequencing

Deep sequencing of recombined T cell receptor (TCR) genes and transcripts has provided a view of T cell repertoire diversity at an unprecedented resolution. Beyond profiling peripheral blood, analysis of tissue-resident T cells provides further insight into immune-related diseases. We describe the e...

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Brown, Scott D., Raeburn, Lisa A., Holt, Robert A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666197/
https://ncbi.nlm.nih.gov/pubmed/26620832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0248-x
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