The PYRIN domain-only protein POP1 inhibits inflammasome assembly and ameliorates inflammatory disease

In response to infections and tissue damage, ASC-containing inflammasome protein complexes are assembled that promote caspase-1 activation, IL-1β and IL-18 processing and release, pyroptosis, and the release of ASC particles. However, excessive or persistent activation of the inflammasome causes inf...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Immunity
Main Authors: de Almeida, Lucia, Khare, Sonal, Misharin, Alexander V., Patel, Rajul, Ratsimandresy, Rojo A., Wallin, Melissa C., Perlman, Harris, Greaves, David R., Hoffman, Hal M., Dorfleutner, Andrea, Stehlik, Christian
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666005/
https://ncbi.nlm.nih.gov/pubmed/26275995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.07.018
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares