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The Changing Role of ER in Endocrine Resistance

Estrogen receptor (ER) is expressed in approximately 70% of newly diagnosed breast tumors. Although endocrine therapy targeting ER is highly effective, intrinsic or acquired resistance is common, significantly jeopardizing treatment outcomes and minimizing overall survival. Even in presence of endoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Breast
Hauptverfasser: Nardone, Agostina, De Angelis, Carmine, Trivedi, Meghana V., Osborne, C. Kent, Schiff, Rachel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666002/
https://ncbi.nlm.nih.gov/pubmed/26271713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2015.07.015
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