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MECHANISMS OF ENDOCRINE RESISTANCE IN BREAST CANCER

The estrogen receptor (ER) pathway plays a pivotal role in breast cancer development and progression. Endocrine therapy to block the ER pathway is highly effective, but its usefulness is limited by common intrinsic and acquired resistance. Multiple mechanisms responsible for endocrine resistance hav...

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Bibliographic Details
Main Authors: Osborne, C Kent, Schiff, Rachel
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656649/
https://ncbi.nlm.nih.gov/pubmed/20887199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-070909-182917
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