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MECHANISMS OF ENDOCRINE RESISTANCE IN BREAST CANCER

The estrogen receptor (ER) pathway plays a pivotal role in breast cancer development and progression. Endocrine therapy to block the ER pathway is highly effective, but its usefulness is limited by common intrinsic and acquired resistance. Multiple mechanisms responsible for endocrine resistance hav...

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Detalhes bibliográficos
Main Authors: Osborne, C Kent, Schiff, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656649/
https://ncbi.nlm.nih.gov/pubmed/20887199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-070909-182917
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