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Endocrinology and hormone therapy in breast cancer: New insight into estrogen receptor-α function and its implication for endocrine therapy resistance in breast cancer

Estrogen and its receptor (ER) are critical for development and progression of breast cancer. This pathway is targeted by endocrine therapies that either block ER functions or deplete ER's estrogen ligand. While endocrine therapies are very effective, de novo and acquired resistance are still c...

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Detalhes bibliográficos
Main Authors: Schiff, Rachel, Osborne, C Kent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242145/
https://ncbi.nlm.nih.gov/pubmed/16168139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1287
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