Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

BACKGROUND. Activation of the NLRP3 inflammasome is associated with metabolic dysfunction, and intermittent fasting has been shown to improve clinical presentation of NLRP3 inflammasome–linked diseases. As mitochondrial perturbations, which function as a damage-associated molecular pattern, exacerba...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Traba, Javier, Kwarteng-Siaw, Miriam, Okoli, Tracy C., Li, Jessica, Huffstutler, Rebecca D., Bray, Amanda, Waclawiw, Myron A., Han, Kim, Pelletier, Martin, Sauve, Anthony A., Siegel, Richard M., Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665779/
https://ncbi.nlm.nih.gov/pubmed/26529255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83260
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