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PTP-PEST Couples Membrane Protrusion and Tail Retraction via VAV2 and p190RhoGAP()

Cell motility is regulated by a balance between forward protrusion and tail retraction. These phenomena are controlled by a spatial asymmetry in signals at the front and the back of the cell. We show here that the protein-tyrosine phosphatase, PTP-PEST, is required for the coupling of protrusion and...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Sastry, Sarita K., Rajfur, Zenon, Liu, Betty P., Côté, Jean-François, Tremblay, Michel L., Burridge, Keith
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664556/
https://ncbi.nlm.nih.gov/pubmed/16513648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600897200
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