Dendritic cells require NIK for CD40-dependent cross-priming of CD8(+) T cells

Dendritic cells (DCs) link innate and adaptive immunity and use a host of innate immune and inflammatory receptors to respond to pathogens and inflammatory stimuli. Although DC maturation via canonical NF-κB signaling is critical for many of these functions, the role of noncanonical NF-κB signaling...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Katakam, Anand K., Brightbill, Hans, Franci, Christian, Kung, Chung, Nunez, Victor, Jones, Charles, Peng, Ivan, Jeet, Surinder, Wu, Lawren C., Mellman, Ira, Delamarre, Lélia, Austin, Cary D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664370/
https://ncbi.nlm.nih.gov/pubmed/26561586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520627112
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