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Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells

Influenza A virus (IAV) infection is normally controlled by adaptive immune responses initiated by dendritic cells (DCs). We investigated the consequences of IAV infection of human primary DCs on their ability to function as antigen-presenting cells. IAV was internalized by both myeloid DCs (mDCs) a...

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Bibliografske podrobnosti
Main Authors: Smed-Sörensen, Anna, Chalouni, Cécile, Chatterjee, Bithi, Cohn, Lillian, Blattmann, Peter, Nakamura, Norihiro, Delamarre, Lélia, Mellman, Ira
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297599/
https://ncbi.nlm.nih.gov/pubmed/22412374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002572
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