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Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells

Influenza A virus (IAV) infection is normally controlled by adaptive immune responses initiated by dendritic cells (DCs). We investigated the consequences of IAV infection of human primary DCs on their ability to function as antigen-presenting cells. IAV was internalized by both myeloid DCs (mDCs) a...

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Autors principals: Smed-Sörensen, Anna, Chalouni, Cécile, Chatterjee, Bithi, Cohn, Lillian, Blattmann, Peter, Nakamura, Norihiro, Delamarre, Lélia, Mellman, Ira
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297599/
https://ncbi.nlm.nih.gov/pubmed/22412374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002572
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