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Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells

Influenza A virus (IAV) infection is normally controlled by adaptive immune responses initiated by dendritic cells (DCs). We investigated the consequences of IAV infection of human primary DCs on their ability to function as antigen-presenting cells. IAV was internalized by both myeloid DCs (mDCs) a...

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Bibliografiske detaljer
Main Authors: Smed-Sörensen, Anna, Chalouni, Cécile, Chatterjee, Bithi, Cohn, Lillian, Blattmann, Peter, Nakamura, Norihiro, Delamarre, Lélia, Mellman, Ira
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297599/
https://ncbi.nlm.nih.gov/pubmed/22412374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002572
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