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Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V
Myosins use a conserved structural mechanism to convert the energy from ATP hydrolysis into a large swing of the force-generating lever arm. The precise timing of the lever arm movement with respect to the steps in the actomyosin ATPase cycle has not been determined. We have developed a FRET system...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664342/ https://ncbi.nlm.nih.gov/pubmed/26553992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517566112 |
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