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Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis

The swinging crossbridge hypothesis states that energy from ATP hydrolysis is transduced to mechanical movement of the myosin head while bound to actin. The light chain-binding region of myosin is thought to act as a lever arm that amplifies movements near the catalytic site. This model has been cha...

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Detalhes bibliográficos
Main Authors: Spudich, James A., Sivaramakrishnan, Sivaraj
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859320/
https://ncbi.nlm.nih.gov/pubmed/20094053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2833
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