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Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers

Plectin is a highly versatile cytoskeletal protein that acts as a mechanical linker between intermediate filament (IF) networks and various cellular structures. The protein is crucial for myofiber integrity. Its deficiency leads to severe pathological changes in skeletal muscle fibers of patients su...

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Bibliographic Details
Published in:Hum Mol Genet
Main Authors: Staszewska, Ilona, Fischer, Irmgard, Wiche, Gerhard
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664173/
https://ncbi.nlm.nih.gov/pubmed/26487297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv438
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