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Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers

Plectin is a highly versatile cytoskeletal protein that acts as a mechanical linker between intermediate filament (IF) networks and various cellular structures. The protein is crucial for myofiber integrity. Its deficiency leads to severe pathological changes in skeletal muscle fibers of patients su...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Staszewska, Ilona, Fischer, Irmgard, Wiche, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664173/
https://ncbi.nlm.nih.gov/pubmed/26487297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv438
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