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Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers

Increasing evidence suggests that the interaction of human islet amyloid polypeptide (hIAPP) with lipids may facilitate hIAPP aggregation and cause the death of pancreatic islet β-cells. However, the detailed hIAPP-membrane interactions and the influences of lipid compositions are unclear. In this s...

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Detalles Bibliográficos
Publicado en:J Diabetes Res
Autores principales: Qian, Zhenyu, Jia, Yan, Wei, Guanghong
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663351/
https://ncbi.nlm.nih.gov/pubmed/26649316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1749196
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