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Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers

Increasing evidence suggests that the interaction of human islet amyloid polypeptide (hIAPP) with lipids may facilitate hIAPP aggregation and cause the death of pancreatic islet β-cells. However, the detailed hIAPP-membrane interactions and the influences of lipid compositions are unclear. In this s...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Qian, Zhenyu, Jia, Yan, Wei, Guanghong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663351/
https://ncbi.nlm.nih.gov/pubmed/26649316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1749196
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