Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives

Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing...

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Bibliographic Details
Published in:J Diabetes Res
Main Authors: Pithadia, Amit, Brender, Jeffrey R., Fierke, Carol A., Ramamoorthy, Ayyalusamy
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662995/
https://ncbi.nlm.nih.gov/pubmed/26649317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2046327
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