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CaMKII-dependent myofilament Ca(2+) desensitization contributes to the frequency-dependent acceleration of relaxation
BACKGROUND: Previous studies suggest that CaMKII activity is required for frequency-dependent acceleration of relaxation (FDAR) in ventricular myocytes. We propose that the underlying mechanism involves CaMKII-dependent regulation of myofilament Ca(2+) sensitivity. METHODS AND RESULTS: Cardiac funct...
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| Publicado no: | Cell Calcium |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662934/ https://ncbi.nlm.nih.gov/pubmed/26297240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2015.08.001 |
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