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Hydrogen Sulfide ameliorates homocysteine-induced Alzheimer's disease-like pathology, blood brain barrier disruption and synaptic disorder

Elevated plasma total homocysteine (Hcy) level is associated with an increased risk of Alzheimer's disease (AD). During transsulfuration pathways, Hcy is metabolized into hydrogen sulfide (H(2)S), which is a synaptic modulator, as well as a neuro-protective agent. However, the role of hydrogen...

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Détails bibliographiques
Publié dans:Mol Neurobiol
Auteurs principaux: Kamat, Pradip K., Kyles, Philip, Kalani, Anuradha, Tyagi, Neetu
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662933/
https://ncbi.nlm.nih.gov/pubmed/26019015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9212-4
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