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Hydrogen Sulfide ameliorates homocysteine-induced Alzheimer's disease-like pathology, blood brain barrier disruption and synaptic disorder

Elevated plasma total homocysteine (Hcy) level is associated with an increased risk of Alzheimer's disease (AD). During transsulfuration pathways, Hcy is metabolized into hydrogen sulfide (H(2)S), which is a synaptic modulator, as well as a neuro-protective agent. However, the role of hydrogen...

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Publicat a:Mol Neurobiol
Autors principals: Kamat, Pradip K., Kyles, Philip, Kalani, Anuradha, Tyagi, Neetu
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662933/
https://ncbi.nlm.nih.gov/pubmed/26019015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9212-4
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