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Hydrogen Sulfide ameliorates homocysteine-induced Alzheimer's disease-like pathology, blood brain barrier disruption and synaptic disorder

Elevated plasma total homocysteine (Hcy) level is associated with an increased risk of Alzheimer's disease (AD). During transsulfuration pathways, Hcy is metabolized into hydrogen sulfide (H(2)S), which is a synaptic modulator, as well as a neuro-protective agent. However, the role of hydrogen...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Kamat, Pradip K., Kyles, Philip, Kalani, Anuradha, Tyagi, Neetu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662933/
https://ncbi.nlm.nih.gov/pubmed/26019015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9212-4
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