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DLL4/Notch1 and BMP9 interdependent signaling induces human endothelial cell quiescence via P27(KIP1) and thrombospondin-1
OBJECTIVE: BMP9/ALK1 and DLL4/Notch promote endothelial quiescence, and we aim to understand mechanistic interactions between the two pathways. We identify new targets that contribute to endothelial quiescence, and test whether loss of Dll4+/− in adult vasculature alters BMP signaling. APPROACH AND...
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| Publicat a: | Arterioscler Thromb Vasc Biol |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662626/ https://ncbi.nlm.nih.gov/pubmed/26471266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306541 |
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