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Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium

Autophagy is an evolutionarily conserved catabolic mechanism that relieves cellular stress by removing/recycling damaged organelles and debris through the action of lysosomes. Compromised autophagy has been implicated in many neurodegenerative diseases, including retinal degeneration. Here we examin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Perusek, Lindsay, Sahu, Bhubanananda, Parmar, Tanu, Maeno, Hiroshi, Arai, Eisuke, Le, Yun-Zheng, Subauste, Carlos S., Chen, Yu, Palczewski, Krzysztof, Maeda, Akiko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661415/
https://ncbi.nlm.nih.gov/pubmed/26468292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682310
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