Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium

Autophagy is an evolutionarily conserved catabolic mechanism that relieves cellular stress by removing/recycling damaged organelles and debris through the action of lysosomes. Compromised autophagy has been implicated in many neurodegenerative diseases, including retinal degeneration. Here we examin...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Perusek, Lindsay, Sahu, Bhubanananda, Parmar, Tanu, Maeno, Hiroshi, Arai, Eisuke, Le, Yun-Zheng, Subauste, Carlos S., Chen, Yu, Palczewski, Krzysztof, Maeda, Akiko
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661415/
https://ncbi.nlm.nih.gov/pubmed/26468292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682310
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы