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Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice

Regeneration of the visual chromophore, 11-cis-retinal, is a crucial step in the visual cycle required to sustain vision. This cycle consists of sequential biochemical reactions that occur in photoreceptor cells and the retinal pigmented epithelium (RPE). Oxidation of 11-cis-retinol to 11-cis-retina...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Sahu, Bhubanananda, Sun, Wenyu, Perusek, Lindsay, Parmar, Vipulkumar, Le, Yun-Zheng, Griswold, Michael D., Palczewski, Krzysztof, Maeda, Akiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646373/
https://ncbi.nlm.nih.gov/pubmed/26391396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682096
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