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An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: NUCLEOTIDE EXCISION REPAIR, DNA DAMAGE CHECKPOINT, AND APOPTOSIS
DNA damage by UV and UV-mimetic agents elicits a set of inter-related responses in mammalian cells, including DNA repair, DNA damage checkpoints, and apoptosis. Conventionally, these responses are analyzed separately using different methodologies. Here we describe a unified approach that is capable...
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Publicado en: | J Biol Chem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661397/ https://ncbi.nlm.nih.gov/pubmed/26438822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.690354 |
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