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Hematopoietic neoplasms in Prkar2a-deficient mice

BACKGROUND: Protein kinase A (PKA) is a holoenzyme that consists of a dimer of regulatory subunits and two inactive catalytic subunits that bind to the regulatory subunit dimer. Four regulatory subunits (RIα, RIβ, RIIα, RIIβ) and four catalytic subunits (Cα, Cβ, Cγ, Prkx) have been described in the...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Saloustros, Emmanouil, Salpea, Paraskevi, Qi, Chen-Feng, Gugliotti, Lina A., Tsang, Kitman, Liu, Sisi, Starost, Matthew F., Morse, Herbert C., Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660639/
https://ncbi.nlm.nih.gov/pubmed/26608815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0257-z
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