Hematopoietic neoplasms in Prkar2a-deficient mice

BACKGROUND: Protein kinase A (PKA) is a holoenzyme that consists of a dimer of regulatory subunits and two inactive catalytic subunits that bind to the regulatory subunit dimer. Four regulatory subunits (RIα, RIβ, RIIα, RIIβ) and four catalytic subunits (Cα, Cβ, Cγ, Prkx) have been described in the...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Saloustros, Emmanouil, Salpea, Paraskevi, Qi, Chen-Feng, Gugliotti, Lina A., Tsang, Kitman, Liu, Sisi, Starost, Matthew F., Morse, Herbert C., Stratakis, Constantine A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660639/
https://ncbi.nlm.nih.gov/pubmed/26608815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0257-z
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