Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects

Osteochondromyxomas (OMX) in the context of Carney complex (CNC) and fibrous dysplasia (FD)-like lesions (FDLL) in mice, as well as isolated myxomas in humans may be caused by inactivation of PRKAR1A, the gene coding for the type 1a regulatory subunit (R1α) of cAMP–dependent protein kinase (PKA). OM...

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Publicado en:Mol Cell Endocrinol
Main Authors: Saloustros, Emmanouil, Liu, Sisi, Mertz, Edward L., Bhattacharyya, Nisan, Starost, Matthew F., Salpea, Paraskevi, Nesterova, Maria, Collins, Michael, Leikin, Sergey, Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123938/
https://ncbi.nlm.nih.gov/pubmed/27498419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.08.004
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