Effect of Mutation Order on Myeloproliferative Neoplasms

BACKGROUND: Cancers result from the accumulation of somatic mutations, and their properties are thought to reflect the sum of these mutations. However, little is known about the effect of the order in which mutations are acquired. METHODS: We determined mutation order in patients with myeloprolifera...

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書誌詳細
出版年:N Engl J Med
主要な著者: Ortmann, Christina A., Kent, David G., Nangalia, Jyoti, Silber, Yvonne, Wedge, David C., Grinfeld, Jacob, Baxter, E. Joanna, Massie, Charles E., Papaemmanuil, Elli, Menon, Suraj, Godfrey, Anna L., Dimitropoulou, Danai, Guglielmelli, Paola, Bellosillo, Beatriz, Besses, Carles, Döhner, Konstanze, Harrison, Claire N., Vassiliou, George S., Vannucchi, Alessandro, Campbell, Peter J., Green, Anthony R.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660033/
https://ncbi.nlm.nih.gov/pubmed/25671252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1412098
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