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X-ray structure and activities of an essential Mononegavirales L-protein domain
The L protein of mononegaviruses harbours all catalytic activities for genome replication and transcription. It contains six conserved domains (CR-I to -VI; Fig. 1a). CR-III has been linked to polymerase and polyadenylation activity, CR-V to mRNA capping and CR-VI to cap methylation. However, how th...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659945/ https://ncbi.nlm.nih.gov/pubmed/26549102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9749 |
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