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Pharmacological Analysis and Structure Determination of 7-Methylcyanopindolol–Bound β(1)-Adrenergic Receptor
Comparisons between structures of the β(1)-adrenergic receptor (AR) bound to either agonists, partial agonists, or weak partial agonists led to the proposal that rotamer changes of Ser(5.46), coupled to a contraction of the binding pocket, are sufficient to increase the probability of receptor activ...
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| Publicado no: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658595/ https://ncbi.nlm.nih.gov/pubmed/26385885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.101030 |
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