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Structure of a β(1)-adrenergic G protein-coupled receptor
G protein-coupled receptors play a major role in transmembrane signalling in higher organisms and many are important drug targets. We report the 2.7 Å resolution crystal structure of a β(1)-adrenergic receptor in complex with the high-affinity antagonist cyanopindolol. The modified turkey receptor h...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923055/ https://ncbi.nlm.nih.gov/pubmed/18594507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07101 |
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