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Structure of a β(1)-adrenergic G protein-coupled receptor

G protein-coupled receptors play a major role in transmembrane signalling in higher organisms and many are important drug targets. We report the 2.7 Å resolution crystal structure of a β(1)-adrenergic receptor in complex with the high-affinity antagonist cyanopindolol. The modified turkey receptor h...

詳細記述

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書誌詳細
主要な著者: Warne, Tony, Serrano-Vega, Maria J., Baker, Jillian G., Moukhametzianov, Rouslan, Edwards, Patricia C., Henderson, Richard, Leslie, Andrew G.W., Tate, Christopher G., Schertler, Gebhard F.X.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923055/
https://ncbi.nlm.nih.gov/pubmed/18594507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07101
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