Phosphorylation of the N-methyl-d-aspartate receptor is increased in the nucleus accumbens during both acute and extended morphine withdrawal

Opioid withdrawal causes a dysphoric state that can lead to complications in pain patients and can propagate use in drug abusers and addicts. Opioid withdrawal changes the activity of neurons in the nucleus accumbens, an area rich in both opioid-binding mu opioid receptors and glutamate-binding NMDA...

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Detaylı Bibliyografya
Yayımlandı:J Pharmacol Exp Ther
Asıl Yazarlar: Anderson, Ethan M., Reeves, Turi, Kapernaros, Katherine, Neubert, John K., Caudle, Robert M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2015
Konular:
Neuropharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658487/
https://ncbi.nlm.nih.gov/pubmed/26377910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.227629
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