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Long-term changes in reward-seeking following morphine withdrawal are associated with altered N-methyl-D-aspartate receptor 1 splice variants in the amygdala

The NR1 subunit of the NMDA receptor can be alternatively spliced by the insertion or removal of the N1, C1, C2, or C2′ regions. Morphine dependence and withdrawal were previously demonstrated to lower N1 and C2′ in the accumbens and lower N1, C1, and C2′ in the amygdala. Withdrawal has also been de...

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Détails bibliographiques
Auteurs principaux: Anderson, Ethan M., Neubert, John K., Caudle, Robert M.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923268/
https://ncbi.nlm.nih.gov/pubmed/22863572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.07.037
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