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Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes

Major Histocompatibility Complex (MHC) genes code for proteins involved in the incitation of the adaptive immune response in vertebrates, which is achieved through binding oligopeptides (antigens) of pathogenic origin. Across vertebrate species, substitutions of amino acids at sites responsible for...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Ejsmond, Maciej Jan, Radwan, Jacek
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658181/
https://ncbi.nlm.nih.gov/pubmed/26599213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004627
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