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Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes

Major Histocompatibility Complex (MHC) genes code for proteins involved in the incitation of the adaptive immune response in vertebrates, which is achieved through binding oligopeptides (antigens) of pathogenic origin. Across vertebrate species, substitutions of amino acids at sites responsible for...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ejsmond, Maciej Jan, Radwan, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658181/
https://ncbi.nlm.nih.gov/pubmed/26599213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004627
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