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MHC allele frequency distributions under parasite-driven selection: A simulation model

BACKGROUND: The extreme polymorphism that is observed in major histocompatibility complex (MHC) genes, which code for proteins involved in recognition of non-self oligopeptides, is thought to result from a pressure exerted by parasites because parasite antigens are more likely to be recognized by MH...

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Main Authors: Ejsmond, Maciej Jan, Babik, Wiesław, Radwan, Jacek
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978226/
https://ncbi.nlm.nih.gov/pubmed/20979635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-332
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