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Evolution of major histocompatibility complex gene copy number

MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show remarkable copy-number variation both between and within species. However, the evolutionary forces driving this variation are poorly understood. Here, we use computer simulations t...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Bentkowski, Piotr, Radwan, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541284/
https://ncbi.nlm.nih.gov/pubmed/31095555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007015
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