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Bacterial metabolites directly modulate farnesoid X receptor activity

BACKGROUND: The farnesoid X receptor (FXR), a ligand-activated transcription factor belonging to the adopted orphan receptor, plays an important role in maintaining health of the liver and intestine. In this study, we identified individual bacterial strains that directly modulated the activation of...

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Bibliografiske detaljer
Udgivet i:Nutr Metab (Lond)
Main Authors: Zhang, Xianqin, Osaka, Toshifumi, Tsuneda, Satoshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657204/
https://ncbi.nlm.nih.gov/pubmed/26604978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-015-0045-y
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