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Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation

Intestinal bacteria play an important role in bile acid metabolism and in the regulation of multiple host metabolic pathways (e.g., lipid and glucose homeostasis) through modulation of intestinal farnesoid X receptor (FXR) activity. Here, we examined the effect of berberine (BBR), a natural plant al...

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Publicat a:Drug Metab Dispos
Autors principals: Tian, Yuan, Cai, Jingwei, Gui, Wei, Nichols, Robert G., Koo, Imhoi, Zhang, Jingtao, Anitha, Mallappa, Patterson, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323626/
https://ncbi.nlm.nih.gov/pubmed/30409838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.118.083691
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