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Bacterial metabolites directly modulate farnesoid X receptor activity

BACKGROUND: The farnesoid X receptor (FXR), a ligand-activated transcription factor belonging to the adopted orphan receptor, plays an important role in maintaining health of the liver and intestine. In this study, we identified individual bacterial strains that directly modulated the activation of...

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Bibliografski detalji
Izdano u:Nutr Metab (Lond)
Glavni autori: Zhang, Xianqin, Osaka, Toshifumi, Tsuneda, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657204/
https://ncbi.nlm.nih.gov/pubmed/26604978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-015-0045-y
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