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Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy

Defects in mitochondrial fusion or fission are associated with many pathologies, raising the hope that pharmacological manipulation of mitochondrial dynamics may have therapeutic benefit. This approach assumes that organ physiology can be restored by rebalancing mitochondrial dynamics, but this conc...

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Pubblicato in:J Cell Biol
Autori principali: Chen, Hsiuchen, Ren, Shuxun, Clish, Clary, Jain, Mohit, Mootha, Vamsi, McCaffery, J. Michael, Chan, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657172/
https://ncbi.nlm.nih.gov/pubmed/26598616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507035
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