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Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy

Defects in mitochondrial fusion or fission are associated with many pathologies, raising the hope that pharmacological manipulation of mitochondrial dynamics may have therapeutic benefit. This approach assumes that organ physiology can be restored by rebalancing mitochondrial dynamics, but this conc...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Chen, Hsiuchen, Ren, Shuxun, Clish, Clary, Jain, Mohit, Mootha, Vamsi, McCaffery, J. Michael, Chan, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657172/
https://ncbi.nlm.nih.gov/pubmed/26598616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507035
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