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Removal of the Mitochondrial Fission Factor Mff Exacerbates Neuronal Loss and Neurological Phenotypes in a Huntington's Disease Mouse Model

Objective: Excessive mitochondrial fission has been associated with several neurodegenerative diseases, including Huntington’s disease (HD). Consequently, mitochondrial dynamics has been suggested to be a promising therapeutic target for Huntington’s disease. Mitochondrial fission depends on recruit...

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Detalhes bibliográficos
Publicado no:PLoS Curr
Main Authors: Cha, Moon Yong, Chen, Hsiuchen, Chan, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149597/
https://ncbi.nlm.nih.gov/pubmed/30279997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.hd.a4e15b80c4915c828d39754942c6631f
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