TDP-43 is intercellularly transmitted across axon terminals

Transactive response DNA-binding protein 43 kD (TDP-43) is an aggregation-prone prion-like domain-containing protein and component of pathological intracellular aggregates found in most amyotrophic lateral sclerosis (ALS) patients. TDP-43 oligomers have been postulated to be released and subsequentl...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Feiler, Marisa S., Strobel, Benjamin, Freischmidt, Axel, Helferich, Anika M., Kappel, Julia, Brewer, Bryson M., Li, Deyu, Thal, Dietmar R., Walther, Paul, Ludolph, Albert C., Danzer, Karin M., Weishaupt, Jochen H.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657165/
https://ncbi.nlm.nih.gov/pubmed/26598621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201504057
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